Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof
AssigneeSolvay Animal Health, Inc.
InventorsGary R. Petersen, K. I. Dayalu
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Abstract
This invention provides a bacterin comprising a virulent Mycoplasma hyopneumoniae isolate, inactivated with binary ethyleneimine, in an amount effective to immunize a swine against infection by Mycoplasma hyopneumoniae and a suitable physiologically acceptable carrier. The invention also provides a method of producing this bacterin. The invention further provides a method of inactivating a virulent strain of Mycoplasma hyopneumoniae by contacting the Mycoplasma hyopneumoniae with binary ethyleneimine. Finally, the invention also provides a method of immunizing swine against infection by Mycoplasma hyopneumoniae comprising administering to the swine a dose of the bacterin so as to immunize the swine.
Claims7
A bacterin comprising virulent Mycoplasma hyopneumoniae isolate 1002 (Strain P-5723-3/ ATCC Accession No. 55088), inactivated with binary ethyleneimine, in an amount not less than 10.sup.9 Mycoplasma hyopneumoniae DNA cell equivalents per milliliter of bacterin, a suitable physiologically acceptable carrier and an adjuvant.
Dependencies are inferred from the claim text.