US 5,564,419 A · Method of photometric in vitro determination of the content of oxygen in a blood sample

Abstract

In a method of photometric in vitro determination of the content of oxygen in a blood sample, a blood sample is transferred directly from an in vivo locality to an at least partially transparent sample container of a sampling device. The sample container has a measuring chamber containing a luminophor, the luminescence of which is quenched in the presence of oxygen. The luminophor is excited by irradiation with radiation from a radiation source. The luminescence emitted by the excited luminophor is detected by a radiation detector and the oxygen content determined on the basis of the radiation detected by the radiation detector. A sampling device and a system for photometric in vitro determination of oxygen in a blood sample are also described.

Claims17

Dependent claims

A method for the photometric in vitro determination of the content of oxygen in a blood sample, comprising:

(a) transferring the blood sample to a sample container:
(i) having an inlet opening and otherwise being essentially sealed;
and
(ii) incorporating a luminophor in a polymer matrix, whose luminescence is quenched in the presence of oxygen;
(b) disposing the sample container in optical communication with an optical system comprising a radiation source and a radiation detector for detecting radiation transmitted from said source;
(c) transmitting radiation from the radiation source to the sample container to excite the luminophor;
(d) transmitting the luminescence emitted by the excited luminophor to the radiation detector;
and
(e) detecting and registering the luminescence.

6 more elements

Dependencies are inferred from the claim text.

Method of photometric in vitro determination of the content of oxygen in a blood sample

Life of this patent

Method of photometric in vitro determination of the content of oxygen in a blood sample

Life of this patent

Abstract

Claims17