Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation

A method for delivering a biological agent into a human or animal's pulmonary system through the human or animal's pulmonary air passages comprising the steps of:

• a) providing an apparatus for delivery of a biological agent comprising a conduit having a proximal end adapted to receive a liquid carrier flow, at least one lumen defining a liquid carrier flow path within the conduit, a distal delivery end adapted for delivering the liquid carrier flow to a device that provides liquid communication to pulmonary air passages, a mechanical means for dispersing a biological agent in the liquid carrier flow path within the conduit comprising a plurality of nozzles disposed in spaced array within the liquid carrier flow path wherein each nozzle has a proximal end adapted to receive biological agent and a distal end adapted for delivering the biological agent as a dispersion in the liquid carrier flow;
• b) introducing the apparatus for delivery of a biological agent into the pulmonary air passages of a human or animal;
• c) establishing a flow of liquid carrier within the liquid carrier flow path;
• d) establishing a flow of biological agent through the nozzles thereby dispersing the biological agent within the liquid carrier flow;
• e) delivering the liquid carrier with dispersed biological agent into the pulmonary air passages of the human or animal.