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US 5,559,266 AGranted
Iodinated esters
AssigneeNycomed Imaging AS
InventorsJo Klaveness, Per Strande
Life of this patent
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Abstract
Water-insoluble iodinated esters of the formula (I) ##STR1## useful in X-ray and ultrasound imaging, are disclosed.
Claims5
A compound which is a water-insoluble iodinated ester of the formula (I):
- ##STR3## in which R.sup.1 is a substituted or unsubstituted C.sub.1-20 aliphatic, C.sub.7-20 -araliphatic or C.sub.6-20 aryl group or a 5 or 6 membered heterocyclic group having one or more hetero atoms selected from O, S and N;
- R.sup.2 is hydrogen or a substituted or unsubstituted C.sub.1-6 aliphatic, C.sub.6-10 aryl or C.sub.7-20 araliphatic group;
- and
- R.sup.3 is a group as defined above for R.sup.1, which may be the same as or different from R.sup.1,
- or R.sup.2 and R.sup.3 together represent a substituted or unsubstituted C.sub.1-4 alkylene group,
- the compound containing at least one iodine atom and being metabolisable to products which are soluble in body fluids and are physiologically acceptable.
3 more elements
Dependencies are inferred from the claim text.