Drug delivery catheter with manifold

A drug delivery catheter for insertion into a vessel which contains a first flowing fluid, the drug delivery catheter comprising:

• an elongated tubular member having a proximal end and a distal end;
• a drug lumen in fluid communication with the distal end of the tubular member for delivering a second fluid;
• a first inflatable balloon assembly disposed at the distal end of the tubular member, the balloon assembly including a tubular balloon helically wound through the elongated tubular member forming a first set of inflatable balloon members having an uninflated state and an inflated state;
• aperture means for delivering the second fluid from said drug lumen to said vessel;
• a second inflatable balloon assembly disposed proximal of the first balloon assembly and separated therefrom by a space, the second balloon assembly including a tubular balloon helically Wound through the elongated tubular member forming a second set of inflatable galloon members having an uninflated state and an inflated state;
• aperture means for delivering the second fluid from said drug lumen to said vessel;
• each of first and second balloon assemblies comprising a sheath attached between each of the balloon members in that respective balloon assembly such that (1) when the first and second sets of balloon members are in an uninflated state, the first fluid in the vessel may flow around the first and second balloon assemblies, and (2) when the first and second sets of balloon members are in an inflated state, sections of the first set of balloon members contact the vessel wall defining a first containment pocket while containing the second fluid between the vessel wall and within the contacting sections of the first balloon assembly, sections of the second set of balloon members contact the vessel wall defining a second containment pocket for containing the second fluid between the vessel wall, the contacting sections of the second balloon assembly and the second sheath, the aperture means being disposed in first and second containment pockets, an inflatable lumen being defined through the interior of the balloon member and sheath of each balloon assembly to allow the first fluid to flow through the balloon member, and the space between the first and second balloon assemblies defining a side opening in the inflatable lumen;
• and
• an inflation lumen in fluid communication with the balloon members for inflating the balloon members.