Organic tissue glue for closure of wounds
AssigneeArch Development Corporation
InventorsJohn Khadem, Toan V. Truong
Life of this patent
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Abstract
The present invention relates generally to the field of biological and medical adhesives and encompasses more specifically the closing of microsurgical wounds and other tissue wounds and defects due to surgical procedures or other causes. A medical adhesive comprising a photosensitizing species and an protein or peptide containing moiety are disclosed which may be applied to various tissues, an adhesive bond being formed by exposure of the adhesive to photoactivating radiation.
Claims34
A composition comprising from about 1% (w/v) to about 50% (w/v) of a biocompatible peptide in solution and in combination with an amount of a flavin photosensitizer capable of producing reactive oxygen species and effective to promote the formation of an adhesive upon photoactivation without more than about 2.degree. C. rise in temperature.
A composition comprising from about 1% (w/v) to about 50% (w/v) of a biocompatible peptide in solution and in combination with an amount of a flavin photosensitizer capable of producing reactive oxygen species and effective to promote the formation of an adhesive upon photoactivation without more than about 2.degree. C. rise in temperature, the combination intended for use as a tissue adhesive.
Dependencies are inferred from the claim text.