Phenylaminocarbonyl derivatives

A compound of formula (1) ##STR9## wherein:

• Y is a halogen atom or a group --OR.sup.1, where R.sup.1 is an optionally substituted straight or branched C.sub.1-3 alkyl group, said R.sup.1 substituent being halogen;
• R.sup.2 is a C.sub.3-8 cycloalkyl group which is optionally substituted with one to three substituents, said R.sup.2 substituents being halogen, C.sub.1-6 alkyl, hydroxyl or C.sub.1-6 alkoxy;
• R.sup.3 is a hydrogen atom;
• R.sup.4 is a pyridinyl group which is optionally substituted with one to four substituents, said R.sup.4 substituents being halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkylenedioxy, C.sub.5-7 cycloalkoxy, haloC.sub.1-6 alkyl, C.sub.1-6 alkylamino, C.sub.1-6 dialkylamino, amino, nitro, cyano, hydroxyl, carboxyl (--CO.sub.2 H), --CO.sub.2 R.sup.7, C.sub.1-6 alkanoyl, sulphonyl (--SO.sub.3 H), C.sub.1-6 alkylsulphonyl, aminosulphonyl (--SO.sub.2 NH.sub.2), C.sub.1-6 alkylaminosulphonyl, C.sub.1-6 dialkylaminosulphonyl, carboxamido (--CONH.sub.2), C.sub.1-6 alkylaminocarbonyl, C.sub.1-6 dialkylaminocarbonyl, sulphonylamino (--NHSO.sub.2 H), C.sub.1-6 alkylsulphonylamino, C.sub.1-6 dialkylsulphonylamino, --NHCOR.sup.8, --NHCSR.sup.8, -13 NHCONH.sub.2, --NHCONHR.sup.7, --NHCON(R.sup.7).sub.2 or C.sub.1-6 alkanoylaminoC.sub.1-6 alkyl;
• each of R.sup.7 and R.sup.8 is independently C.sub.1-6 alkyl, C.sub.6-12 aryl or C.sub.6-12 arylC.sub.1-3 alkyl;
• X is --O--;
• n is zero or an integer of value 1;
• or a salt, solvate or hydrate thereof.

A compound of formula (2) ##STR10## wherein:

• R.sup.3 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.6-12 aryl or C.sub.6-12 arylC.sub.1-6 group;
• R.sup.4 is a pyridinyl group which is optionally substituted with one to four substituents, said R.sup.4 substituents being halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkylenedioxy, C.sub.5-7 cycloalkoxy, haloC.sub.1-6 alkyl, C.sub.1-6 alkylamino, C.sub.1-6 dialkylamino, amino, nitro, cyano, hydroxyl, carboxyl (--CO.sub.2 H), --CO.sub.2 R.sup.7, C.sub.1-6 alkanoyl, sulphonyl (--SO.sub.3 H), C.sub.1-6 alkylsulphonyl, aminosulphonyl (--SO.sub.2 NH.sub.2), C.sub.1-6 alkylaminosulphonyl, C.sub.1-6 dialkylaminosulphonyl, carboxamido (--CONH.sub.2), C.sub.1-6 alkylaminocarbonyl C.sub.1-6 dialkylaminocarbonyl, sulphonylamino (--NHSO.sub.2 H), C.sub.1-6 alkylsulphonylamino C.sub.1-6 dialkylsulphonylamino, --NHCSR.sup.8, --NHCSR.sup.8, --NHCONH.sub.2, --NHCONHR.sup.7, --NHCON(R.sup.7).sub.2 or C.sub.1-6 alkanoylaminoC.sub.1-6 alkyl;
• each of R.sup.7 and R.sup.8 is independently C.sub.1-6 alkyl, C.sub.6-12 aryl or C.sub.6-12 arylC.sub.1-3 alkyl;
• n is zero or an integer of value 1, 2 or 3;
• or a salt, solvate or hydrate thereof.

A compound which is selected from the group consisting of:

• N-(3-Cyclopentyloxy-4-methyloxyphenyl)-4-pyridinecarboxamide;
• and
• N-(3-Cyclopentyloxy-4-methyloxyphenyl)-1,2-benzenedicarboxamide;
• N-Benzoyl-3-cyclopentyloxy-4-methyloxyaniline;
• Methyl-2-N-(3-Cyclopentyloxy-4-methyloxyphenyl)-3,5-dichloro-4-pyridinecarb oxamide;
• or a salt, solvate or hydrate thereof.