Antiviral, spermicidal vaginal gel and foam containing low molecular weight povidone-iodine
OwnerEdward Shanbrominventor
Life of this patent
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Abstract
A virucidal, spermicidal vaginal gel consisting essentially of povidone iodine having a povidone to iodine ratio of about 15:1 or higher containing from about one percent to about twenty percent low molecular weight povidone having a molecular weight of about 20 kd or lower, the gel having a viscosity such that a conical body drawn from a body of the same does not visibly slump at 37C. for a period of at least one minute and a method of preventing sexual transmission of disease and preventing pregnancy using the same are disclosed.
Claims4
A virucidal, spermicidal vaginal gel consisting essentially of water, povidone and iodine wherein the weight ratio of povidone to iodine is at least 15 to 1 and wherein the povidone contains between 1 and 25 percent povidone having a molecular weight at least as low as 20 kd, said gel having a viscosity such that a conical body drawn from said gel does not visibly slump for a period of about one minute at 37 degrees celsius.
A virucidal, spermicidal vaginal gel consisting essentially of:
- a) a powder consisting essentially of a mixture, based on a total of 20 weight parts of 1), 2) and 3), of
- 1) 10 parts by weight povidone iodine comprising about 85 percent by weight povidone having a molecular weight range of about 30 to about 50 kd, 10 percent iodide and 5 percent iodine;
- 2) 5 parts by weight povidone having a molecular weight range of 30 to 50 kd;
- and 3) 5 parts by weight povidone having a molecular weight at least as low as 20 kd;
- to which b) sufficient water has been added to produce a gel having about 2.5 weight percent iodine based on the weight of the entire gel, said gel having a viscosity such that a conical body drawn from said gel does not visibly slump for a period of about one minute at 37 degrees celsius.
A method of preventing transmission of sexually transmitted diseases comprising the step of introducing to the vagina, prior to intercourse, a vaginal gel or foam consisting essentially of water, povidone and iodine wherein the weight ratio of povidone to iodine is at least 15 to 1 and wherein the povidone contains between 1 and 25 weight percent povidone having a molecular weight at least as low as 20 kd, said gel or foam having a viscosity such that a conical body drawn from the gel or foam does not visibly slump for a period of about one minute at 37 degrees celsius.
Dependencies are inferred from the claim text.