1,3-oxathiolane nucleoside compounds and compositions
AssigneeBioChem Pharma Inc.
InventorGervais Dionne
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Abstract
The invention relates to 1,3-oxathiolane nucleoside analogues and their use in the treatment of viral infections. More specifically, this invention relates to (-)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidi n-2-one and pharmaceutically acceptable derivatives and pharmaceutical formulations thereof.
Claims5
(-)-C is-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin- 2-one or a pharmaceutically acceptable salt, ester or salt of an ester thereof.
The substantially pure (-)-enantiomer of cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidi n-2-one or a pharmaceutically acceptable salt, ester or salt of an ester thereof, wherein the (+) enantiomer is present in an amount of no more than 5% w/w.
Dependencies are inferred from the claim text.