Oral treatment of helicobacter infection
AssigneeOraVax, Inc.
InventorsSteven J. Czinn, John G. Nedrud
Life of this patent
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Abstract
Method of eliciting in a mammalian host a protective immune response to Helicobacter infection, by orally administering to the host an immunogenically effective amount of Helicobacter antigen. Vaccine compositions are also provided.
Claims5
A method of eliciting in a mammalian host a protective immune response to Helicobacter infection, comprising orally adminstering to the host an immunogenically effective amount of Helicobacter antigen with a mucosal adjuvant to elicit said protective immune response, wherein the Helicobacter antigen is a whole cell lystate preparation of at least one Helicobacter felis and Helicobacter pylori.
A vaccine composition comprising an immunogenically effective amount of a whole cell lysate of Helicobacter antigen and a mucosal adjuvant in association with a pharmaceutically acceptable carrier or diluent, wherein the Helicobacter antigen is a whole cell lysate preparation of at least one of Helicobacter felis and Helicobacter pylori.
Dependencies are inferred from the claim text.