Use of piperine to increase the bioavailability of nutritional compounds
AssigneeSabinsa Corporation
InventorsMuhammed Majeed, Vladimir Badmaev, R. Rajendran
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Abstract
A new composition and method for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the composition comprises an extract from the fruit of Piper containing a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.
Claims28
A composition suitable for improving gastrointestinal absorption and systemic utilization of nutritional materials, subsequent increase in nutrient induced thermogenesis, and increase in lean body mass comprising at least one nutritional material in a nutritionally effective amount and an extract from the fruits of family Piperaceae comprising at least 98% of alkaloid piperine wherein the piperine is present in a therapeutically effective amount such that a daily dose consists of 0.004 to 0.08 mg/kg of body weight.
A method for improving gastrointestinal absorption and systemic utilization of nutritional materials, subsequent increase in nutrient induced thermogenesis, and increase in lean body mass;
- said method comprising administering to a subject in need thereof a composition containing at least one nutritional material in a nutritionally effective amount, and an extract from the fruit of piper comprising at least 98% of alkaloid piperine in a therapeutically effective amount such that a daily dose consists of 0.004 to 0.08 mg/kg of body weight.
Dependencies are inferred from the claim text.