US 5,532,372 A · Imide derivatives, and their production and use

Abstract

An imide compound of the formula: ##STR1## wherein Z is a group of the formula: ##STR2## in which the substituents are defined herein, and n is an integer of 0 to 1; D is a group of the formula: --(CH.sub.2).sub.p --A--(CH.sub.2).sub.q -- in which A is a non-aromatic hydrocarbon ring optionally bridged with a lower alkylene group or an oxygen atom, said non-aromatic hydrocarbon ring and said lower alkylene group being each optionally substituted with at least one lower alkyl, and p and q are each an integer of 0, 1 or 2; and Ar is an aromatic group, a heterocyclic aromatic group, a benzoyl group, a phenoxy group or a phenylthio group and G is >N--, >CH-- or >COH-- or Ar is a biphenylmethylidene group and G is >C.dbd., all of the above groups being each optionally substituted with at least one of lower alkyl, lower alkoxy and halogen; and its acid addition salts, useful as an antipsycotic agent.

Claims20

Dependent claims

An imide compound of the formula:

##STR144## wherein Z is a group of the formula:
##STR145## in which B is a carbonyl group or a sulfonyl group, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each a hydrogen atom or an alkyl group having 1-4 carbon atoms with a proviso that R.sup.1 and R.sup.2 or R.sup.1 and R.sup.3 are combined together to make a non-aromatic hydrocarbon ring having at most 7 carbon atoms and being un-substituted or substituted with at least one alkyl group having 1-4 carbon atoms, and n is an integer of 0 or 1;
D is a group of the formula:
--(CH.sub.2).sub.p --A--(CH.sub.2).sub.q --
in which A is a non-aromatic hydrocarbon ring having at most 7 carbon atoms or a non-aromatic hydrocarbon ring having at most 7 carbon atoms which is bridged with an alkylene group having not more than 3 carbon atoms or an oxygen atom, and p and q are each an integer of 0, 1 or 2;
Ar is a benzisothiazolyl group being unsubstituted or substituted with at least one of an alkyl group having 1-4 carbon atoms, an alkoxy group having 1-4 carbon atoms and a halogen atom;
and G is >N--;
or an acid addition salt thereof.

5 more elements

Dependencies are inferred from the claim text.

Imide derivatives, and their production and use

Life of this patent

Imide derivatives, and their production and use

Life of this patent

Abstract

Claims20