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US 5,523,490 AGranted
Illudin analogs
AssigneeThe Regents of the University of California
InventorsMichael J. Kelner, Trevor C. McMorris, Raymond Taetle
Life of this patent
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Abstract
A compound to inhibit tumor cell growth in a subject in need of said therapy is provided, wherein said compound has the structure: ##STR1## wherein R is selected from the group consisting of: ##STR2## Tumor cells sensitive to inhibition by said compound are selected from the group consisting of a myeloid leukemia cell, a T-cell leukemia cell, a lung carcinoma cell, an ovarian carcinoma cell, and a breast carcinoma cell.
Claims7
A compound of the formula:
- ##STR19## wherein R is selected from the group consisting of:
- ##STR20##
Dependencies are inferred from the claim text.