Benzamide derivatives and pharmaceutical composition comprising the same

A compound of the formula:

• ##STR25## wherein R.sup.1 is hydrogen or lower alkyl, R.sup.2 is hydrogen, lower alkyl, halo(lower) alkyl, halogen or lower alkoxy,
• R.sup.3 and R.sup.4 are each hydrogen, lower alkyl or taken together to form oxo,
• R.sup.5 is hydrogen, halogen, nitro, hydroxy, protected hydroxy, lower alkyl, or lower alkoxy optionally substituted with lower alkylamino or di(lower)alkyl amino,
• R.sup.6 is hydrogen, lower alkyl or acyl,
• R.sup.7 is hydrogen;
• lower alkyl optionally substituted with halogen, amino, lower alkylamino, di(lower)alkylamino, protected amino, acyl, a heterocyclic group, hydroxy or protected hydroxy;
• or acyl;
• Y is ##STR26## wherein R.sup.14 is hydrogen, halogen, hydroxy or lower alkoxy;
• R.sup.15 is aryloxy, naphthyl, phenyl substituted with substituent(s) selected from the group consisting of lower alkyl, lower alkoxy, halogen, halo(lower)alkyl, hydroxy, amino(lower)alkyl, azido(lower)alkyl, lower alkylamino(lower)alkyl, di(lower)alkylamino(lower)alkyl, acylamino(lower)alkyl, hydroxy(lower)alkyl, cyano and acyl, or a heterocyclic group, and
• R.sup.16 is aryl;
• and
• n is 0, 1, 2 or 3,
• and pharmaceutically acceptable salts thereof.