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AssigneeMallinckrodt Medical, Inc.
InventorsDennis L. Nosco, Sandeep Nema, Alexander L. Klibanov, Kofi Adzamli
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The present invention provides new and structurally diverse particulates for use in magnetic resonance imaging and X-ray contrast imaging of body organs and tissues having the following general formula: Ca.sub.n M.sub.m X.sub.r Y.sub.s wherein M is a paramagnetic ion or stoichiometric mixture of metal ions having a valence of 2+ or 3+; X is a simple anion; Y is a tetrahedral oxyanion, or mixtures thereof; m is an integer greater than or equal to 1; n is an integer greater than or equal to 1; r and s are integers and are adjusted as needed to provide charge neutrality; and further comprising a polyalkoxy compound. Methods for using and making particles of the invention are also disclosed.
A diagnostic agent comprising a compound of the general formula:
A diagnostic agent comprising a compound of the general formula:
A method of imaging comprising administering to a patient a compound of the general formula:
A method of imaging comprising administering to a patient a compound of the general formula:
Dependencies are inferred from the claim text.