US 5,516,921 AGranted

Thiono-lactone inhibitors of protein trafficking and uses therefor

AssigneeARIAD Pharmaceuticals, Inc.

InventorsManfred Weigele, Mallory F. Loewe, Christopher S. Poss

Life of this patent

Estimating the term…

Abstract

Novel compounds related structurally to Brefeldin A useful as antiviral, antifungal, antiproliferative, immunosuppresive and detoxifying agents as well as pharmaceutical compositions and methods based thereon are disclosed.

Claims3

Dependent claims

A compound of the formula:

##STR23## wherein Y is a carbon-carbon (trans) double bond or a cyclopropyl ring and Z is ##STR24##

Dependencies are inferred from the claim text.

Facts

Application: 08/308,184Filed 19 Sep 1994 · continuation in part
Priority: 27 Jan 1994
Granted: 14 May 1996
Term ends: Not estimatedThe source records don’t support an estimate.

Classification3 codes

C07D 225/04
Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom: condensed with…
C07D 313/00
Heterocyclic compounds containing rings of more than six members having one oxygen
C07D
Heterocyclic compounds

Family

Serial188,083Parent of this continuation-in-part · filed 27 Jan 1994
Serial193,820Parent of this continuation-in-part · filed 9 Feb 1994
Serial207,319Parent of this continuation-in-part · filed 7 Mar 1994
Serial207,496Parent of this continuation-in-part · filed 7 Mar 1994
US 5,516,921 AThis patent

From the US filing history. Foreign family members aren’t listed.

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