Xanthone derivatives, their preparation and use
AssigneeInverni Della Beefa S.p.A.
InventorsPaolo Da Re, Giorgio Pifferi, Piero Valenti, Salvatore Malandrino
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Abstract
The novel compounds 3,6-Disubstituted xanthen-9-one of formula I ##STR1## in which R is a C.sub.3 -C.sub.8 linear, branched or cyclic alkyl and R.sub.1 is linear, branched C.sub.1 -C.sub.8 alkyl or cyclic C.sub.3 -C.sub.8 alkyl or --OR in which R is as defined hereinabove, exhibit bone resorption inhibiting activity. Pharmaceutical compositions are described.
Claims6
A 3,6-Disubstituted xanthen-9-one of formula I ##STR4## wherein R is a C.sub.3 -C.sub.8 linear, branched or cyclic alkyl and R.sub.1 is linear, branched C.sub.1 -C.sub.8 alkyl or cyclic C.sub.3 -C.sub.8 alkyl or --OR in which R is as defined hereinabove.
A method of treatment of a living subject affected by bone resorption which consists of administering orally an effective amount of a 3,6-Disubstituted xanthen-9-one of formula I ##STR6## wherein R is a C.sub.3 -C.sub.8 linear branched or cyclic alkyl and R.sub.1 is linear, branched C.sub.1 -C.sub.8 alkyl or cyclic C.sub.3 -C.sub.8 alkyl or --OR in which R is as defined hereinabove.
Dependencies are inferred from the claim text.