Agent for treating high blood pressure and cardiac insufficiency

A method of treating cardiac insufficiency in a warm-blooded animal which comprises administering to said animal a therapeutically effective amount of a compound of formula ##STR4## wherein A is a --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, ##STR5## wherein R.sub.7 is an alkyl group having 1 to 3 carbon atoms, and B is a methylene or carbonyl group or

• A is a --CO--CO-- group and B is a methylene group,
• E is an ethylene, n-propylene or n-butylene group optionally substituted by an alkyl group with 1 to 3 carbon atoms, an n-propylene group substituted by a hydroxy group in the 2 position or an n-butylene group substituted by a hydroxy group in the 2 or 3 position,
• G represent a methylene or ethylene group optionally substituted by an alkyl group with 1 to 3 carbon atoms,
• R.sub.1 and R.sub.2, which may be identical or different, are hydroxy groups, alkyl, alkoxy or phenylalkoxy groups in which the alkyl moiety may contain from 1 to 3 carbon atoms, or one of the groups R.sub.1 or R.sub.2 may also represent a hydrogen atom or R.sub.1 together with R.sub.2 is an alkylenedioxy group with 1 or 2 carbon atoms,
• R.sub.3 and R.sub.4, which may be identical or different, are hydrogen or halogen atoms, hydroxy groups, alkyl or alkoxy groups each having 1 to 4 carbon atoms, trifluoromethyl or cyano groups or one of the groups R.sub.3 or R.sub.4 is a nitro group or R.sub.3 together with R.sub.4 is an alkylenedioxy group with 1 or 2 carbon atoms,
• R.sub.5 is a hydrogen atom, an alkyl, hydroxy, alkoxy, amino, alkylamino, dialkylamino, alkanoylamino, alkoxycarbonylamino or bis(alkoxycarbonyl)amino group wherein the alkyl part may contain from 1 to 3 carbon atoms, or a methylamino or ethylamino group substituted by a trifluoromethyl group, and
• R.sub.6 is a hydrogen atom, an alkyl, phenylalkyl, alkanoyl or alkoxycarbonyl group in which the alkyl moiety may contain from 1 to 3 carbon atoms or an alkylene group with 3 to 5 carbon atoms.
• and the physiologically acceptable acid addition salts thereof with inorganic or organic acids.