Dietary phytoestrogen in estrogen replacement therapy
AssigneesWake Forest University, Protein Technologies International, Inc.
InventorsClaude L. Hughes, Edna C. Henley, Thomas B. Clarkson
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Abstract
Disclosed is a pharmaceutical composition for oral delivery. The composition includes about 1-2 mg mammalian estrogen and about 25-100 mg phytoestrogen. Compositions of the type described above are utilized, for example, in a therapeutic regimen designed to reduce the risk of coronary heart disease and osteoporosis in postmenopausal women. This method comprises the oral administration of a composition comprising a mixture of estrogen and phytoestrogen, the dosages of mammalian estrogen and phytoestrogen being about 1-2 mg, about 25-100 mg, respectively.
Claims19
A pharmaceutical composition for oral delivery comprising a combination of mammalian estrogen and soy-derived phytoestrogen in an amount sufficient to reduce the risk of coronary heart disease and osteoporosis in women.
A method for reducing the risk of coronary heart disease and osteoporosis in women, the method comprising administering orally a combination of mammalian estrogen and soy-derived phytoestrogen in a therapeutically effective amount.
An estrogen replacement therapy regimen, comprising the oral coadministration of a combination of mammalian estrogen and soy-derived phytoestrogen in a therapeutically effective amount.
Dependencies are inferred from the claim text.