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AssigneeOtsuka Pharmaceutical Factory, Inc.
InventorsAkio Kawamura, Motoki Yonekawa, Osamu Kaneko, Hiroshi Kamogawa
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In a plasma filtration process including a treatment with a primary filter for separating blood into blood cells and plasma and a treatment with a secondary filter for removing harmful macromolecules from the separated plasma for purification, the secondary filter is washed by passing a washing liquid through an inner chamber of the filter, an outer chamber thereof or both the chambers in an amount corresponding to 5 to 50% of the priming volume of the filter every time the filtration pressure has reached 70 to 100% of the withstanding pressure of the secondary filter. This washing procedure reduces the time required for the filtration of plasma to about 60 to 70% of the time conventionally needed, shortens the patient restraining time, and decreases the amount of washing liquid to be used to consequently diminish the disposal loss of plasma from the system.
In a plasma filtration process including a treatment of blood with a primary filter for separating the blood into blood cells and plasma and a treatment of the separated plasma with a secondary filter having an inner chamber and an outer chamber so as to remove harmful macromolecules from the separated plasma for purification where the secondary filter is intermittently washed with a wash liquor, a method of washing the secondary filter comprising the step of passing a wash liquor through at least one of the inner chamber and the outer chamber of the secondary filter in an amount corresponding to 5 to 50% of a priming volume of the secondary filter every time filtration pressure reaches at least 350 to 500 mm Hg wherein a withstanding pressure for the secondary filter is at least 500 mm Hg.
Dependencies are inferred from the claim text.