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US 5,516,395 AGranted
Process for the production of collagen foams in the form of continuous tapes and their use in medicine, cosmetics and hygiene
AssigneeLTS Lohmann Therapie-Systeme AG
InventorsDieter Anhauser, Michael Roreger
Life of this patent
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Abstract
The present invention relates to a process for the production of collagen foams in the form of continuous tapes, characterized in that a) solved or dispersed collagen is cast into disk molds, b) the collagen solution or dispersion is frozen in the disk mold and subsequently is freeze-dried c) continuous tapes are produced from the freeze-dried disks by mechanical processes. Furthermore, the present invention relates to the use of said tapes so obtained in medicine, cosmetic and hygiene.
Claims12
A process for the production of a collagen foam in the form of a plurality of continuous tapes, comprising
- a) casting dissolved or dispersed native uncross-linked collagen manufactured from animal skin into a disk mold to a height of about 0.5 to 10 cm,
- b) shock-freezing the collagen solutions or dispersions in the disk mold to a temperature of -50.degree. C. or lower at a rate of at least about 30.degree. C./hour, and then freeze-drying under vacuum, thereby forming a plurality of homogeneous sponges having very fine pores and disc shapes, and
- c) placing the discs side by side vertically on a hub and mechanically peeling a plurality of continuous tapes from the freeze-dried collagen on a tape peeling machine.
Dependencies are inferred from the claim text.