Use of retinoids and compositions containing same for hair growth
OwnerGail S. Bazzanoinventor
Life of this patent
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Abstract
Increase in the rate of hair growth, stimulation of hair follicles to produce new hair growth, prolongation of the anagen phase of the hair cycle, and conversion of vellus hair to growth as terminal hair, and treatment of alopecias due to organic dysfunction of the hair follicle is attained in mammalian skins by either oral administration or by topical application to the skin, hair and/or hair follicles of the mammal of effective amounts of a retinoid, particularly retinoic acid. The retinoid may be administered or applied alone or with other adjunctive compounds including vitamins, such as Vitamin D.sub.3, hormones, antiandrogens and/or vasodilators.
Claims36
A method for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises topically applying to the scalp a retinoid in an amount which is effective to increase the rate of hair growth.
A method for treating alopecia caused by a shortening of the anagen phase of the hair cycle which comprises topically applying to the scalp all-trans retinoic acid in an amount which is effective to increase the rate of hair growth.
A method for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises topically applying to the scalp a retinoid in an amount which is effective to stimulate hair follicles of said scalp to produce hair growth therefrom.
A method for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises topically applying to the scalp a retinoid in an amount which is effective to prolong the anagen phase of the hair cycle.
A method for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises topically applying to the scalp a retinoid in an amount which is effective to convert vellus hair to growth as terminal hair.
A method of increasing the rate of hair growth on mammalian skins which comprises topical or oral administration to the mammal of a retinoid in an amount which is effective to increase the rate of hair growth.
A method of retarding shedding in fur bearing animals comprising topical or oral administration to the animal of an effective amount of a retinoid.
A method of retarding molting in birds comprising topical or oral administration to the bird of an effective amount of a retinoid.
A composition for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises a retinoid in admixture with Vitamin D.sub.3 or a Vitamin D.sub.3 derivative selected from the group consisting of 1-hydroxycholecalciferol;
- 1,25-dihydroxycholecalciferol;
- and 1,24-dihydroxycholecalciferol, said admixture being in an amount which is effective to increase the rate of hair growth.
A composition for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises a retinoid in admixture with a hormone selected from the group consisting of estrogens and progesterones, said admixture being in an amount which is effective to increase the rate of hair growth.
A composition for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises a retinoid in admixture with an antiandrogen selected from the group consisting of cyproterone acetate, spironolactone, secosteroids, flutamides, cyoctol, and decahydro-7H-benz(E)-inden-7-ones, said admixture being in an amount which is effective to increase the rate of hair growth.
A composition for treating alopecias caused by a shortening of the anagen (growing) phase of the hair cycle, which comprises a retinoid in admixture with a peripheral circulatory system vasodilator which increases the blood supply to the microvasculature around the hair follicles of the scalp, said admixture being in an amount which is effective to increase the rate of hair growth.
Dependencies are inferred from the claim text.