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AssigneeThe United States of America as represented by the Secretary of Commerce
InventorMichael J. Tarlov
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A process for creating a two dimensional spacial distribution pattern of ferent thiolate molecules on a substrate by illuminating a surface of a self-assembled monolayer of a first thiolate compound in the presence of oxygen with high frequency electromagnetic radiation distributed according to a desired pattern, and subsequently immersing the illuminated substrate in a solution of a second thiolate compound so that molecules of the first thiolate compound in illuminated areas of the monolayer are exchanged for molecules of said second thiolate compound; and a patterned biomolecular composite formed of a substrate which forms a self-assembled thiolate monolayer when immersed in a solution of a thiolate forming compound, a thiolate monolayer deposited on the substrate and composed of patterned areas of first and second thiolate compounds, respectively, the first thiolate compound having an affinity for specifically or nonspecifically adsorbing a biological molecule, and the second thiolate compound having essentially no affinity for the biological molecule, and at least one biological material adsorbed in a corresponding pattern on the patterned areas of the first thiolate compound in the thiolate monolayer.
A process for creating a pattern comprising a two dimensional spacial distribution of thiolate compound molecules in a self-assembled monolayer formed on a substrate, said process comprising the steps of:
A process for controlling chemical and physical properties of selected areas of a surface capable of forming a thiol self-assembled monolayer according to a predetermined pattern, said process comprising the steps of:
A process for selectively applying biological molecules to a surface, comprising the steps of:
Dependencies are inferred from the claim text.