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US 5,512,683 AGranted
Alkyl or alkoxy substituted S-heterocyclic retinoids
AssigneeHoffmann-La Roche Inc.
InventorsMichael Klaus, Peter Mohr
Life of this patent
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Abstract
Compounds of the formula ##STR1## in which X is --S--, --SO-- or --SO.sub.2 --; R.sup.1 is C.sub.7-10 -alkyl or C.sub.7-10 -alkoxy; R.sup.2 is a residue of the formula ##STR2## R.sup.3 is carboxy or lower-alkoxycarbonyl; and n is an integer of 1, 2 or 3; and salts of carboxylic acids of formula I can be used for the treatment of autoimmune diseases and diseases having a strong immunological component, such as psoriasis.
Claims16
A fused bicyclic compound of the formula:
- ##STR13## wherein X is --S--, --SO-- or --SO.sub.2 --;
- R.sup.1 is C.sub.7-10 -alkyl or C.sub.7-10 -alkoxy;
- R.sup.2 is a residue of the formula ##STR14## and R.sup.3 is carboxy or lower-alkoxycarbonyl;
- or salts of said bicyclic compound when R.sup.3 is carboxy.
1 more element
Dependencies are inferred from the claim text.