Back to results
US 5,512,566 AGranted
Tricyclic compounds having affinity for the 5-HT1A receptor
AssigneeOrtho Pharmaceutical Corporation
InventorsEllen W. Baxter, Allen B. Reitz
Life of this patent
Estimating the term…
Abstract
Compounds represented by the general formula I: ##STR1## are disclosed as useful in treating diseases of the central nervous system.
Claims10
A compound represented by the formula I:
- ##STR12## wherein R.sup.1 and R.sup.2 are independently selected from any of H, halogen, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkyl or trifluoromethyl;
- X is O when n is 1 and X is NH when n is 0;
- wherein Y is CH.sub.2 ;
- wherein n is 0 or 1;
- wherein Z is N when X is O and Z is C when X is NH;
- wherein R.sup.3 and R.sup.4 are independently selected from any of H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.8 acyl, provided that R.sup.3 and R.sup.4 can not both be C.sub.1 -C.sub.8 acyl at the same time or may be taken together to form with the N a monocyclic 5-7 membered saturated ring or a 5 membered ring fused to an aromatic ring;
- or the racemates, individual isomers, hydrates, solvates or acid addition salts thereof.
4 more elements
Dependencies are inferred from the claim text.