Dye compositions and methods for film coating tablets and the like
AssigneeWarner-Jenkinson Company, Inc.
InventorsCharles A. Signorino, Harry Meggos
Life of this patent
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Abstract
An improved dye composition for use in coating tablets and the like is constituted by a stable, aqueous suspension containing a water-soluble, nontoxic dye, an opacifying agent which may be titanium dioxide or iron oxide all immobilizing agent for immobilizing the dye and preventing it from migrating when applied to a tablet or the like, the immobilizing agent being constituted by a nontoxic metal salt present in an amount of from approximately 0.1 to 10 equivalents of metal per mole of dye, and water. The suspension may also contain a film-forming, water-soluble or water-dispersible edible polymer and a plasticizer. These compositions are used in lieu of lake compositions to produce tablets and the like with uniform, non-mottled coatings.
Claims19
The method of producing a smooth, uniform, substantially non-mottled coating on tablets which comprises the steps of:
- (a) preparing a stable, aqueous suspension comprising a water-soluble, nontoxic dye, an opacifying agent selected from the group consisting of titanium dioxide and iron oxide, a nontoxic immobilizing agent constituted by a metal salt in an amount of from approximately 0.1 to approximately 10 equivalents of metal per mole of dye, and water;
- (b) mixing said stable, aqueous suspension with an aqueous solution of a film-forming, water-soluble or water-dispersible, edible polymer to form an aqueous coating suspension;
- and
- (c) applying said coating suspension onto tablets or the like whereby said nontoxic immobilizing agent immobilizes said dye and substantially prevents it from migrating, thereby producing a smooth, uniform, substantially non-mottled coating on said tablets or the like.
The method of producing a smooth, uniform, substantially non-mottled coating on tablets which comprises the steps of:
- (a) preparing a stable, aqueous coating suspension comprising a water-soluble, nontoxic dye, an opacifying agent selected from the group consisting of titanium dioxide and iron oxide, a nontoxic immobilizing agent constituted by a metal salt in an amount of from approximately 0.1 to approximate 10 equivalents of metal per mole of dye, a film-forming, water-soluble or water-dispersible, edible polymer, and water;
- and
- (b) applying said coating suspension onto tablets or the like whereby said nontoxic immobilizing agent immobilizes said dye and substantially prevents it from migrating, thereby producing a smooth, uniform, substantially non-mottled coating on said tablets or the like.
The method of 12 wherein said nontoxic metal salt is selected from the group consisting of calcium and magnesium salts.
Dependencies are inferred from the claim text.