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US 5,510,517 AGranted
Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids
AssigneeMerck & Co., Inc.
InventorsRichard R. Dauer, Lisa DiMichele, Mauricio Futran, Gerard R. Kieczykowski
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Abstract
A process for continuously producing alkylpyrophosphonate, alkylpyrophosphate and multimers thereof and for producing 4-amino-1-hydroxyalkylidene-1,1-bisphosphonic acids or salts thereof.
Claims5
A compound of the structural Formula I
- Z--R.sub.1
- I
- wherein Z is selected from the group consisting of:
- a) H.sub.2 N--C.sub.2-5 alkyl--;
- R.sub.1 is:
- ##STR20## wherein X is --OH or Cl.
3 more elements
Dependencies are inferred from the claim text.