Anti-hypertensive composition and methods of treatment
AssigneeUniversity of Florida Research Foundation, Inc.
InventorRaymond J. Bergeron, Jr.
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Abstract
Pharmaceutical compositions for the treatment of hypertension comprising an effective anti-hypertensive amount of at least one compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient, the compound having one of the formulae (I), or (II), and methods for the treatment of hypertension or effecting anti-hypertensive action which comprises administering to a patient requiring anti-hypertensive therapy or effect at least one of the above-described compounds.
Claims10
A method of effecting anti-hypertensive action which comprises administering to a patient requiring anti-hypertensive effect at least one compound having one of the formulae:
- ##STR2## wherein:
- R and R' may be the same or different and are H, alkyl or aralkyl having from 1 to 12 carbon atoms;
- R.sub.1 -R.sub.6 may be the same or different and are H, R or R';
- m and n may be the same or different and are integers from 3 to 10, inclusive;
- a-e may be the same or different and are integers from 3 to 10, inclusive;
- or
- (III) a salt of (I) or (II) with a pharmaceutically acceptable acid.
Dependencies are inferred from the claim text.