Methods of using (+) doxazosin for the treatment of hypertension
AssigneeSepracor Inc.
InventorNancy M. Gray
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Abstract
Methods are disclosed utilizing the optically pure (+) isomer of doxazosin. This compound is a potent drug for the treatment of hypertension while avoiding the concomitant liability of adverse effects associated with the racemic mixture of doxazosin.
Claims8
A method for treating hypertension in a human while avoiding the concomitant liability of adverse effects associated with racemic doxazosin, which comprises administering to a human, in need of antihypertensive therapy, an amount of (+) doxazosin, or a pharmaceutically acceptable salt thereof, substantially free of its (-) stereoisomer, said amount being sufficient to alleviate said hypertension but insufficient to cause said adverse effects.
Dependencies are inferred from the claim text.