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US 5,510,330 AGranted
Combinations of thrombolytically active proteins and non-heparin anticoagulants, and uses thereof.
AssigneeBoehringer Mannheim GmbH
InventorsUlrich Martin, Stephan Fischer
Life of this patent
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Abstract
The invention involves thromboembolically effective compositions and therapeutic methods. Thrombolytically active proteins are combined with anticoagulants, as long as the anticoagulant is not heparin. The anticoagulant is administered in an intravenous bolus form, while the thrombolytically active protein may be administered via intravenous bolus, or intravenous infusion.
Claims10
Method for treating a subject in need of thrombolytic therapy, comprising administering to said subject an effective amount of:
- (i) BM 06.022, which consists of SEQ ID NO:
- 1 and
- (ii) via bolus injection, hirudin.
Dependencies are inferred from the claim text.