Preparations for the treatment of eyes
AssigneeRamot University for Applied Research and Industrial Development Ltd.
InventorsMichael Belkin, Naphtali Savion, Nahum Landshman
Life of this patent
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Abstract
The invention relates to compositions which induce in humans regeneration of the corneal endothelium. The compositions of the invention are of value in regenerating the corneal endothelium in humans, which is frequently damaged in the course of eye surgery and injuries. Such regeneration is very important to ensure the full functionality of the eye. The compositions of the invention comprise as active ingredient an adequate quantity of fibroblast growth factor (FGF) in a suitable physiologically acceptable vehicle. A preferred embodiment of the invention relates to a composition containing a certain quantity of hyaluronic acid and any other viscoelastic agent.
Claims20
A method for enhancing the regeneration of the corneal endothelium in an eye of a human patient in need of said regeneration, comprising administering one injection into the anterior chamber of said human eye of an effective quantity of a composition containing a fibroblast growth factor in a physiologically acceptable carrier.
A method for protecting the corneal endothelium in the eye of a human patient in need of said protection against degeneration caused by surgery to the eye, comprising administering one injection into the anterior chamber of said eye of an effective quantity of a composition containing a fibroblast growth factor in a physiologically acceptable carrier.
A method for enhancing healing of the corneal endothelium in a human patient needing treatment for an injured or diseased eye comprising administering one injection into the anterior chamber of said injured or diseased eye of an effective quantity of a composition containing a fibroblast growth factor in a physiologically acceptable carrier.
A method for enhancing regeneration of transplanted corneal endothelium tissue which has been transplanted into the eye of a human patient comprising injecting into the anterior chamber of said eye an effective amount to enhance regeneration of said transplanted corneal endothelium tissue of a preparation containing fibroblast growth factor in a physiologically acceptable carrier.
Dependencies are inferred from the claim text.