Compositions that inhibit wound contraction and methods of using same
AssigneeLa Jolla Cancer Research Foundation
InventorsJames Polarek, Richard Tamura, John Harper
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Abstract
The present invention provides methods for reducing or inhibiting wound contraction in a subject having a wound comprising administering to the subject a pharmaceutical composition comprising a peptide or a polypeptide. The invention provides, for example, a method of reducing or inhibiting wound contraction comprising the administration of a pharmaceutical composition comprising a peptide having more than three consecutive basic amino acids. The invention also provides a method of reducing or inhibiting wound contraction comprising the administration of a pharmaceutical composition comprising decorin.
Claims2
A method for reducing or inhibiting wound contraction in a mammalian subject, comprising administering to said mammalian subject a pharmaceutical composition, comprising decorin and a pharmacologically acceptable carrier.
Dependencies are inferred from the claim text.