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US 5,508,464 AGranted
Process for the preparation of 5,6-dihydroxyindole and intermediate compounds
AssigneeL'oreal
InventorsAlex Junino, Jean J. Vandenbossche, Gerard Lang
Life of this patent
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Abstract
Process for the preparation of 5,6-dihydroxyindole, wherein the compound of formula: ##STR1## in which R' denotes a hydrogen atom or an optionally substituted benzyl radical, is subjected either to the action of hydrogen under pressure or to a hydrogen transfer operation, in a solvent medium and in the presence of a hydrogenation catalyst.
Claims3
A process for preparing a compound of the formula
- wherein R' represents benzyl, said process comprising reacting 4,5-dihydroxyphenylacetonitrile having the formula ##STR7## with benzyl halide in the presence of a solvent and in an alkaline medium so as to obtain 4,5-dibenzyloxyphenylacetonitrile of the formula ##STR8## and subjecting said 4,5-dibenzyloxyphenylacetonitrile to a nitration reaction so as to prepare said compound of formula II, above.
Dependencies are inferred from the claim text.