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US 5,508,444 AGranted
Cyclic compounds
AssigneeZeneca Limited
InventorsAndrew J. Blacker, Martin Brown, Martin C. Bowden
Life of this patent
Estimating the term…
Abstract
Novel substituted cis-1,2-dihydroxy-cyclohexadiene compounds, useful as intermediates in the production of compounds for use as intermediates in the production of agrochemicals and pharmaceuticals, and a microbial process for the preparation thereof.
Claims13
A cyclohexadiene compound of formula (I) or (II) ##STR9## wherein A is C(O)--O--R where R is alkyl linked to the ring or R by the carboxylic group, or A is CN;
- R.sup.1 is lower alkylene in formula (II) and methylene in formula (I) both optionally carrying one or more non-interfering substituents;
- R.sup.2 is O or NH or NR.sup.3 ;
- R.sup.3 is C.sub.1-4 alkyl;
- X is a non-interfering substituent;
- Z is an optional group comprising a 5- or 6-membered carbocyclic ring which is optionally substituted;
- m is 0 or 1;
- and n is 0-3;
- provided that when A is CN and n is 0 and Z is not present, then R.sup.1 is methylene and m is 1, and further provided that when m is 0, and Z is not present, the carboxylic ester is not --C(O)--O-tertiary-butyl.
5 more elements
Dependencies are inferred from the claim text.