Antigenized antibodies and genes
AssigneeThe Regents of the University of California
InventorsMaurizio Zanetti, Maurizio Sollazzo
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Abstract
Antibodies have been recombinantly produced which contain the NANP tetrapeptide of Plasmodium Falciparum within their third complementarity determining region in N-terminus of the variable region. These antibodies are capable of eliciting an antibody response.
Claims3
An immunoglobulin molecule containing a tetrapeptide Asn-Ala-Asn-Pro epitope within the third complementarity-determining region in the N-terminus variable domain thereof, said immunoglobulin molecule having the effector function conferred by the constant region of the immunoglobulin, wherein said tetrapeptide is capable of eliciting an antibody response.
Dependencies are inferred from the claim text.