Azole derivative and pharmaceutical composition
AssigneeKureha Chemical Industry Co., Ltd.
InventorsKoichi Niimura, Takao Ando, Toyohiko Nitta, Yuko Ikeda
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Abstract
A novel azole derivative of the general formula (I): ##STR1## wherein R.sub.1 and R.sub.2 are, independently from each other, a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, x.sub.1 and x.sub.2 are, independently from each other, a hydrogen or halogen atom, or hydroxyl, cyano, or trifluoromethyl group, and Y is CH or a nitrogen atom, a process for the production thereof, and a pharmaceutical composition containing the same as the active ingredient.
Claims14
A method of inhibiting aromatase, comprising administering to a mammal in need thereof a pharmaceutical composition comprising an effective aromatase inhibiting amount of a compound of formula (I):
- ##STR10## wherein X.sub.1 is a chlorine or fluorine atom, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.