Method and system for optimizing dialysis clearance
AssigneeBaxter International Inc.
InventorPrakash R. Keshaviah
Life of this patent
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Abstract
A system and method using same are provided for determining the optimum operating conditions of a dialysis process that yields the highest whole body dialysis clearance. The system varies a parameter that effects dialysis efficiency during part of a dialysis run. The system then measures a metabolite concentration in an outflow dialysate. The system develops a metabolite concentration profile as a function of the varied parameter. Based on these measurements, the system correlates the metabolite concentration measurements to determine the optimum parameter setting that yields the maximum metabolite concentration.
Claims19
A method for obtaining the highest whole body dialysis clearance in a dialysis system comprising the steps of:
- varying a parameter that effects dialysis efficiency during part of a dialysis run;
- measuring a metabolite concentration in an outflow dialysate;
- developing a metabolite concentration profile as a function of the varied parameter from the metabolite concentration measurements;
- and
- correlating the metabolite concentration measurements to determine an optimum parameter setting that yields a maximum metabolite concentration.
A method for determining the optimum blood pump setting of a dialysis system to obtain the highest whole body dialysis clearance comprising the steps of:
- varying a blood flow rate during a dialysis run;
- measuring a metabolite concentration in an outflow dialysate;
- developing a metabolite concentration profile as a function of the blood flow rate;
- and
- correlating the metabolite concentration measurements to determine an optimum blood flow rate setting that yields a maximum metabolite concentration.
A system for obtaining the highest whole body dialysis clearance in a dialysis system comprising:
- means for varying a parameter that effects dialysis efficiency during part of a dialysis run;
- means for measuring a metabolite concentration in an outflow dialysate;
- means for developing a metabolite concentration profile as a function of the varied parameter;
- and
- means for correlating the metabolite concentration measurements to determine an optimum parameter setting that yields a maximum metabolite concentration.
Dependencies are inferred from the claim text.