Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use
AssigneeMinnesota Mining and Manufacturing Company
InventorsGeorge G. I. Moore, Richard M. Flynn, Miguel A. Guerra
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Abstract
This invention relates to physiologically acceptable emulsions of perfluorocarbon ether hydrides having 8 to 12 carbon atoms. These novel emulsions have various medical applications. They are especially useful medically as contrast media for various biological imaging modalities such as nuclear magnetic resonance, .sup.19 F-magnetic resonance imaging, ultrasound, x-ray, and computed tomography, as oxygen transport agents or "artificial bloods" in the treatment of heart attack, stroke, and other vascular obstructions, as adjuvants to coronary angioplasty and in cancer radiation treatment and chemotherapy.
Claims19
A physiologically acceptable aqueous emulsion comprising
- a saturated C.sub.8 to C.sub.12 perfluorocarbon ether hydride selected from the group consisting of a hydroperfluoroaliphatic ether, a hydroperfluoroaliphatic ether substituted with a perfluoroalicyclic group, and a hydroperfluorocycloaliphatic ether and mixtures thereof, wherein said aliphatic ether has a straight-chain or a branched-chain of carbon atoms,
- water and a surfactant, wherein the components are contained in the emulsion in amounts for acceptable physiological administration.
Dependencies are inferred from the claim text.