4-oxoquinoline-3-carboxylic acid derivatives their preparation and their use
AssigneesSankyo Company, Limited, Ube Industries, Ltd.
InventorsMasayuki Iwata, Tomio Kimura, Teruhiko Inoue, Yoshimi Fujihara, Tetsushi Katsube
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Abstract
Compounds of formula (I): ##STR1## (in which: R.sup.1 represents fluorinated methoxy: R.sup.2 represents a nitrogen-containing heterocyclic group and R.sup.3 represents hydrogen or amino) and pharmaceutically acceptable salts, esters and amides thereof are valuable antibacterial agents, which may be prepared by reacting a compound similar to that of formula (I) but in which R.sup.2 is replaced by a halogen atom with a compound providing the required group R.sup.2.
Claims15
A compound of the formula ##STR20## wherein R.sup.1 is a fluorinated methoxy group, R.sup.10a is a hydrogen atom or a C.sub.1 -C.sub.6 alkyl group and R.sup.3a is a hydrogen atom, a nitro group or an amino group.
A compound of the formula ##STR21## wherein R.sup.1 is a fluorinated methoxy group and R.sup.3a is a hydrogen atom or an amino group.
Dependencies are inferred from the claim text.