Methods of inhibiting cell-cell adhesion
AssigneeEli Lilly and Company
InventorBrian W. Grinnell
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Abstract
A method of inhibiting cell-cell adhesion comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Claims3
A method to inhibit inflammatory and disrupted normal coagulation process in patients with disorders of the vascular endothelium comprising administering to a patent in need thereof an effective amount of a compound having the formula ##STR5## wherein R.sup.1 and R.sup.3 are independently hydrogen, ##STR6## wherein Ar is optionally substituted phenyl;
- R.sup.2 is selected from the group consisting of pyrrolidine, hexamethylenemino, and piperidino;
- or a pharmaceutically acceptable salt of solvate thereof.
Dependencies are inferred from the claim text.