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US 5,496,847 AGranted
Aminomethyl-benzodioxane and benzopyran serotonergic agents
AssigneeBristol-Myers Squibb Company
InventorsJohn D. Catt, Ronald J. Mattson
Life of this patent
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Abstract
Certain aminomethyl-benzodioxanes and benzopyrans are useful serotonergic agents. They possess anxiolytic properties with few of the side effects often associated with dopaminergic agents.
Claims8
A compound of Formula I or a pharmaceutically acceptable salt, amide or hydrate thereof:
- ##STR9## wherein:
- R.sup.1 and R.sup.2 are both halogen or, taken together, form a --O--(CH.sub.2).sub.n --O-- bridge (n=1, 2 or 3);
- Cy is either ##STR10## (m=0, 1 or 2), with the phenyl substituent at the 1 position of the cycloalkanyl or cycloalkenyl ring and the amino substituent at the 4 position;
- and
- R.sup.3 and R.sup.4 are independently H or C.sub.1-4 alkyl.
2 more elements
Dependencies are inferred from the claim text.