Back to results
US 5,496,846 AGranted
Taxol treatment of breast cancer
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsWyndham H. Wilson, Robert Wittes
Life of this patent
Estimating the term…
Abstract
The present invention is a method of treatment for a patient with cancer. In particular, it is a method of treating patients having breast cancer using the microtubule agent, Taxol. The present method of administration, serves to prevent or retard the adverse side effects associated with Taxol and reduces the chances of a patient developing mdr Taxol resistance. The novel method of treatment provides a low-dose, longterm exposure to Taxol in a patient.
Claims1
A method of treating a patient suffering from breast cancer, which comprises:
- (a) intravenously infusing taxol into said patient at a continuous dosage rate of between 17.5 to 35 milligrams of taxol per square meter of patient surface area per 24 hours to infuse between 70 and 140 milligrams of taxol per square meter of patient surface area into said patient over a period of 96 hours;
- and
- (b) repeating said step (a) in 21 day cycles until remission of said patient's breast cancer is obtained.
Dependencies are inferred from the claim text.