Indole derivatives

An indole derivative of the general formula ##STR414## wherein R.sup.1 is a halogen atom, R.sup.2 is a hydrogen atom, a lower alkyl group, a lower alkanoyl group or a benzoyl group, R.sup.3 is a hydrogen atom, a lower alkyl group or a halogen atom, R.sup.4 is a group of the formula ##STR415## in which R.sup.6 is a lower alkyl group, a cycloalkyl group, a phenyl group which may optionally have a lower alkyl group as a substituent, a phenyl-lower alkyl group or a pyridyl group, R.sup.7 is a hydrogen atom or a lower alkyl group, Q is a sulfur or selenium atom and n is an integer of 0 to 2, A is an alkylene group, m is an integer of 0 to 1, R.sup.5 is a hydrogen atom, an alkyl group or a benzoyl group having a hydroxyl group or a group of the formula --O--B--R.sup.8 in which B is a lower alkylene group and R.sup.8 is a phenyl, di-lower alkyl-amino, 1-pyrrolidinyl, piperidino, 1-imidazolyl or 1,2,4-triazol-1-yl group as a substituent when m is 0 or, when m is 1, R.sup.5 is a lower alkoxycarbonyl group, a carboxyl group, a hydroxyl group, a group of the formula --C(.dbd.O)--N(R.sup.9)--R.sup.10 in which R.sup.9 and R.sup.10 are the same or different and each is a hydrogen atom, a lower alkyl group, a cycloalkyl group which may optionally have a benzene ring fused or condensed thereto, a phenyl group, a phenyl-lower alkyl group or a lower alkylsulfonyl group or R.sup.9 and R.sup.10 are bound to each other either directly or via an oxygen or sulfur atom to form, together with the adjacent nitrogen atom, a heterocyclic group which may optionally be substituted with a lower alkoxycarbonyl or carboxyl group, a group of the formula --CH.sub.2 --N(R.sup.11)--R.sup.12 in which R.sup.11 and R.sup.12 are the same or different and each is a hydrogen atom, a lower alkyl group, a cycloalkyl group which may optionally have a benzene ring condensed thereto, a phenyl group, a phenyl-lower alkyl group or a lower alkanoyl group or R.sup.11 and R.sup.12 are bound to each other either directly or via an oxygen or sulfur atom to form, together with the adjacent nitrogen atom, a heterocyclic group which may optionally be substituted with a lower alkoxycarbonyl or carboxyl group, a group of the formula --OR.sup.13 in which R.sup.13 is a lower alkylcarbamoylphenyl group, a lower alkylaminomethylphenyl group, a lower alkylaminomethylpenyl group, a 1-pyrrolidinylcarbonylphenyl group, a 1-pyrrolidinylmethylphenyl group, a 2-di-lower alkylaminoethyl group or a 2-hydroxyl-2-lower alkylaminoethyl group or a phenyl group which may optionally have a hydroxyl, lower alkoxy, 1-pyrrolidinylcarbonyl or 1-pyrrolidinylmethyl group as a substituent, and x is an integer of 0 to 2.