Ophthalmic use of S-timolol hemihydrate
OwnerMarkku Pera/ lampiinventor
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Abstract
A novel composition and method for making compositions containing S-timolol hemihydrate having the formula: ##STR1## wherein the compositions are useful as pharmaceutical agents for topical administration to an eye for treating glaucoma and/or lowering intraocular pressure.
Claims19
An Ophthalmic topical composition containing a therapeutically effective amount of (S)-(-)-3-morpholino-4-( 3-tert-butyl-amino-2 hydroxypropoxy)-1, 2,5-thiadiazole hemihydrate together with an ophthalmic carrier.
Method for the topical treatment of glaucoma and ocular hypertension which comprises administering to the eye of a human or animal in need of such treatment a therapeutically effective amount of (S)-(-)-3-morpholino-4-(3-tert-butyl-amino-2 hydroxypropoxy)-1,2,5-thiadiazole hemihydrate.
Process for the pharmaceutically treating a subject with (S)-(-)-3-morpholino-4-(3-tert-butyl-amino-2 hydroxypropoxy)-1,2,5-thiadiazole hemihydrate comprising the steps of:
- preparing a composition containing an intraocular pressure effective lowering amount of (S)-(-)-3-morpholino-4-(3-tert-butyl-amino-2 hydroxypropoxy)-1,2,5-thiadiazole hemihydrate;
- and
- topically applying the prepared composition to the eye of the subject.
A pharmaceutical composition for topical ophthalmic application to the eye of a subject containing an intraocular pressure lowering effective amount of (S)-(-)-3-morpholino-4-(3-tert-butyl-amino-2-hydroxypropox)-1,2,5-thiadiaz ole hemihydrate wherein the composition is in a dosage form.
Dependencies are inferred from the claim text.