Glycoside compounds and production and use thereof
AssigneeR. Erich Klemke
InventorR. Erich Klemke
Life of this patent
Estimating the term…
Abstract
Novel glycosides 7-ketosteryl di-O-acyl-pyranoside and 7-.beta.-hydroxycholesteryl 2,3-dideoxy-.alpha.-D-erythro-hex-2-enopyranoside. The glycosides possess valuable pharmacological properties as a medicament. In particular, the cholesterol glycoside in vivo exhibits a selective cell-destructive activity on malignant cells which activity is substantially free of side effects on normal cells. The glycosides possess useful properties, especially pharmacological properties which are the same as the respective unglycosylated aglycon.
Claims4
A 3.beta.,7.beta.-dihydroxysteryl 2,3-dideoxy-.alpha.-D-erythro-hex-2-enopyranoside compound of formula ##STR7##
A 3.beta.-hydroxy 7-ketosteryl 4,6-di-O-acyl-2,3-dideoxy-.alpha.-D-erythro-hex-2-enopyranoside of formula ##STR8## where Acyl is a lower acyl group.
A medicament for inhibiting the growth of neoplastic cells which comprises in pharmaceutically acceptable dosage form an effective neoplastic cell growth inhibiting amount of a 3.beta.7.beta.-dihydroxypyranoside of formula ##STR9## in a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.