Porous solid formulations containing proteinaceous physiologically active substances
AssigneeSumitomo Pharmaceuticals Company, Limited
InventorsKeiji Fujioka, Shigeji Sato, Yoshihiro Takada
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Abstract
A solid formulation for buccal or oral administration which contains a proteinaceous physiologically active substance as an active ingredient, as well as collagen and a water-soluble additive, said formulation being characterized by being porous and having a good disintegration property, and a preparation thereof are provided.
Claims8
A spongy formulation for buccal or oral administration which contains a therapeutically effective amount of a proteinaceous physiologically active substance as an active ingredient, collagen and a water-soluble additive, said formulation being characterized by having a density of 10 mg/cm.sup.3 to 500 mg/cm.sup.3, a porosity of from 99% to 23% and a disintegration time of from 1 minute to 30 minutes.
A spongy formulation for treating AIDS, which is suitable for buccal or oral administration, and which contains a therapeutically effective amount of interferon as an active ingredient, collagen and a water-soluble additive, said formulation being characterized by having a density of 10 mg/cm.sup.3 to 500 mg/cm.sup.3, a porosity of from 99% to 23% and a disintegration time of from 1 minute to 30 minutes.
A spongy formulation for preventing the progress of AIDS, which is suitable for buccal or oral administration, and which contains a therapeutically effective amount of interferon as an active ingredient, collagen and a water-soluble additive, said formulation being characterized by having a density of 10 mg/cm.sup.3 to 500 mg/cm.sup.3, a porosity of from 99% to 23% and a disintegration time of from 1 minute to 30 minutes.
Dependencies are inferred from the claim text.