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US 5,496,551 AGranted
Peptide structures, immunogens containing them and their uses in the control of fertility
AssigneeLafon Pharma S.A.
InventorsJean-Michel Bidart, Dominique Bellet, Claude Bohuon
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Abstract
The subject of the present invention is a peptide structure comprising at least the sequence 106-116 of a .beta.-CG or a .beta.-LH a sequence of at least 5 amino acids containing at least one lysine residue. These structures may be used for the preparation of vaccines intended to control fertility.
Claims12
A peptide of the sequence:
- Thr Met Leu Val Gln Lys Asn Val Thr Ser bonded to the sequence 106-116 of .beta.-hCG.
A peptide of the sequence:
- Thr Met Leu Val Gln Lys Asn Val Thr Ser His Pro Leu Thr Cys Asp Asp Pro Arg Phe Gln Tyr Gly-CONH.sub.2.
A synthetic immunogen of the sequence:
- Thr Met Leu Val Gln Lys Asn Val Thr Ser His Pro Leu Thr Cys Asp Asp Pro Arg Phe Gln coupled to a protein carrier.
A synthetic immunogen of the sequence:
- Thr Met Leu Val Gln Lys Asn Val Thr Ser His Pro Leu Thr Cys Asp Asp Pro Arg Phe Gln Tyr Gly-CONH.sub.2 coupled by a bisdiazo benzidine to a protein carrier.
Dependencies are inferred from the claim text.