Phosphate-binding polymers for oral administration
AssigneeGelTex Pharmaceuticals, Inc.
InventorsStephen R. Holmes-Farley, W. Harry Mandeville, III, George M. Whitesides
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Abstract
Phosphate-binding polymers are provided for removing phosphate from the gastrointestinal tract. The polymers are orally administered, and are useful for the treatment of hyperphosphatemia.
Claims18
A method for removing phosphate from a patient by ion exchange comprising orally administering to said patient a therapeutically effective amount of a composition comprising at least one polymer characterized by a repeat unit having the formula ##STR28## or a copolymer thereof, wherein n is an integer and each R, independently, is H or a lower alkyl, alkylamino, or aryl group.
A method for removing phosphate from a patient by ion exchange comprising orally administering to said patient a therapeutically effective amount of a composition comprising at least one polymer characterized by a repeat unit having the formula ##STR29## or a copolymer thereof, wherein each n is an integer, each R, independently, is H or a lower alkyl, alkylamino, or aryl group, and each X.sup.- is an exchangeable negatively charged counterion.
A therapeutic composition for removing phosphate from a patient by ion exchange comprising a therapeutically effective amount of at least one polymer characterized by a repeat unit having the formula ##STR31## or copolymer thereof, wherein n is an integer and each R, independently, is H or a lower alkyl, alkylamino, or aryl group.
Dependencies are inferred from the claim text.