Fluorocarbon contrast media for use with MRI and radiographic imaging
AssigneeAlliance Pharmaceutical Corp.
InventorW. Dean Kirkland
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Abstract
This invention relates to a non-aqueous fluorocarbon composition for use in magnetic resonance imaging (MRI) or radiographic imaging (X-ray or computed tomography), particularly imaging of the gastrointestinal (GI) tract. The invention also relates to an improved fluorocarbon composition with enhanced contrast effects in the GI tract. This invention further discloses an improved fluorocarbon composition having improved palatability. The invention further provides improved preparations for radiographic imaging or MRI. Methods for producing and using such preparations are disclosed, as are methods for improving the palatability of non-aqueous liquids. Finally, methods for improving imaging are disclosed.
Claims23
A composition for use with in vivo imaging systems, a fluorocarbon liquid and an effective amount of a solid fluorocarbon-insoluble particulate material, selected from the group consisting of a gas-generating, palatability-enhancing, and pharmacological, agent, in direct admixture with said liquid.
A method for making a non-aqueous composition for use with imaging systems, comprising suspending in a fluorocarbon liquid an effective amount of a solid fluorocarbon-insoluble particulate material selected from the group consisting of a gas-generating, palatability-enhancing, and pharmacological, in direct admixture with said liquid.
Dependencies are inferred from the claim text.