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US 5,495,001 AGranted
Recombinant purified protease nexin
AssigneeIncyte Pharmaceuticals, Inc.
InventorsMichael P. McGrogan, Randy W. Scott, Joffre B. Baker, Christian C. Simonsen, Sr.
Life of this patent
Estimating the term…
Abstract
DNA segments encoding two slightly different protease nexin I forms (PN-I.alpha. and PN-I.beta.) are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.
Claims3
Purified protease nexin-I.alpha. having an amino acid sequence as shown in FIGS. 3A, 3B and 3C.
Purified unglycosylated protease nexin-I having the amino acid sequence as shown in FIGS. 3A, 3B, and 3C or FIGS. 4A, 4B and 4C.
Dependencies are inferred from the claim text.